T. Chapman

Socially plastic responses in females are robust to evolutionary manipulations of adult sex ratio and adult nutrition

This study tests if female Drosophila fecundity plasticity evolves predictably under different adult sex ratios and nutrition, but finds robustness to these manipulations.

Nutritional insensitivity to mating in male fruit flies

This study shows that male fruit flies do not change their diet choice after multiple matings, unlike females, despite physiological costs.

Natural mutations of human XDH promote the nitrite (NO2-)-reductase capacity of xanthine oxidoreductase: a novel mechanism to promote redox health?

This study examines how natural mutations in human XDH affect XOR activity, revealing varied impacts on UA, ROS, and NO production, and suggests potential therapeutic strategies for cardiovascular disease.

Developmental diet alters the fecundity-longevity relationship and age-related gene expression in Drosophila melanogaster

This study shows that larval diet quality in Drosophila melanogaster alters the directionality of fecundity-longevity relationships and affects age-related gene expression.

Eusocial insect queens show costs of reproduction and transcriptomic signatures of reduced longevity

The paper experimentally shows that eusocial insect queens experience costs of reproduction, evidenced by reduced longevity and transcriptomic changes related to aging.

Experimental evolution under varying sex ratio and nutrient availability modulates male mating success in Drosophila melanogaster

This study shows that sex ratio and nutrition interact to affect pre-copulatory mating traits in Drosophila melanogaster but act independently on post-copulatory traits.

Characterisation of the symbionts in the Mediterranean fruitfly gut

The paper characterizes the gut microbiome of the Mediterranean fruitfly, identifying Klebsiella oxytoca as a dominant symbiont with potential nutritional benefits to the host.

Female fruitflies use gustatory cues to exhibit reproductive plasticity in response to the social environment

The paper shows that female fruitflies adjust their reproductive behavior based on social environment through gustatory cues, not olfactory or visual cues.

Reproductive plasticity in both sexes interacts to determine mating behaviour and fecundity

This study investigates how reproductive plasticity in both sexes of Drosophila melanogaster interacts to influence mating behavior and fecundity, showing that these interactions can affect fitness outcomes.

Multigenerational downregulation of insulin/IGF-1 signalling in adulthood improves lineage survival, reproduction, and fitness in C. elegans supporting the developmental theory of ageing

Transmission efficiency drives host-microbe associations

The paper models how different transmission modes affect host-microbe associations and finds that mixed transmission modes are most effective.

Transgenerational fitness effects of lifespan extension by dietary restriction in Caenorhabditis elegans

This study examines the transgenerational effects of dietary restriction on lifespan and fitness in C. elegans, finding both benefits and detriments across generations.

Ataxin-3 links NOD2 and TLR2 mediated innate immune sensing and metabolism in myeloid cells

This study identifies ataxin-3 as a mediator of NOD2 and TLR2 signaling in myeloid cells, linking innate immune sensing to metabolic processes and mitochondrial function.

NOD2 and TLR2 Signal via TBK1 and PI31 to Direct Cross-presentation and CD8 T Cell Responses

This study identifies TBK1 and PI31 as key mediators of NOD2 and TLR2 signaling in dendritic cells, enhancing cross-presentation and CD8+ T cell responses against bacterial pathogens.

Response to a Synthetic Pheromone Source by OX4319L, a Self-Limiting Diamondback Moth (Lepidoptera: Plutellidae) Strain, and Field Dispersal Characteristics of Its Progenitor Strain

Mate choice and gene expression signatures associated with nutritional adaptation in the medfly (Ceratitis capitata)

The paper examines gene expression changes in medflies under nutritional selection and links them to mate choice behavior across generations.

Vertically transmitted rhabdoviruses are found across three insect families and have dynamic interactions with their hosts

The paper identifies vertically transmitted rhabdoviruses in three insect species and shows they spread rapidly through host populations with high maternal transmission rates.