Author

D. Muraro

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

L. Vallier· 2 shared A. J. Butler· 1 shared A. J. Collier· 1 shared A. M. Moon· 1 shared A. Osnato· 1 shared A. P. Davenport· 1 shared A. Simmons· 1 shared A. W. Lohse· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCell Biology

L. Vallier

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

TGFβ signalling is required to maintain pluripotency of human naïve pluripotent stem cells

A. Osnato, S. Brown, C. Krueger, S. Andrews, A. J. Collier, S. Nakanoh, M. Quiroga Londono, B. T. Wesley, D. Muraro, S. Brumm, K. Niakan, L. Vallier, D. Ortmann, P. J. Rugg-Gunn

This study shows that TGFβ signalling maintains naive human pluripotency by regulating SMAD2/3 binding and gene expression, with distinct effects compared to primed hPSCs.

bioRxiv · Jul 10, 2021Cell Biology

FXR inhibition reduces ACE2 expression, SARS-CoV-2 infection and may improve COVID-19 outcome

T. Brevini, M. Maes, G. J. Webb, W. T. H. Gelson, S. Forrest, P. Mlcochova, S. Dillon, S. Varankar, M. Darvish-Damavandi, V. L. Mulcahy, R. E. Kuc, T. L. Williams, V. Galanakis, M. Vila-Gonzalez, O. C. Tysoe, , F. Sampaziotis

This study shows FXR inhibition lowers ACE2 expression, reduces SARS-CoV-2 infection, and correlates with better clinical outcomes in COVID-19.

bioRxiv · Jun 6, 2021 · PreprintMicrobiology

NOD2 and TLR2 Signal via TBK1 and PI31 to Direct Cross-presentation and CD8 T Cell Responses

D. Corridoni, S. Shiraishi, T. Chapman, T. Steevels, D. Muraro, M.-L. Thezenas, G. Prota, J.-L. Chen, U. Gileadi, N. Ternette, V. Cerundolo, A. Simmons

This study identifies TBK1 and PI31 as key mediators of NOD2 and TLR2 signaling in dendritic cells, enhancing cross-presentation and CD8+ T cell responses against bacterial pathogens.

bioRxiv · Mar 8, 2019Immunology