Cell BiologybioRxiv
High affinity interactions and signal transduction between Aβ oligomers and TREM2
C. B. Lessard, S. L. Malnik, Y. Zhou…·T. Golde
This study investigates the high-affinity interaction between TREM2 and Aβ oligomers, showing that AD-associated TREM2 variants have reduced signaling and internalization capacity.
DOI 10.15252/emmm.201809027