STING activation promotes autologous type I interferon-dependent development of type 1 regulatory T cells during malaria
Y. Wang, F. Rivera, C. Edwards, T. Frame, J. A. Engel, L. Bukali, J. Na, S. Ng, D. Corvino, M. Montes de Oca, P. Bunn, M. Soon, D. Andrew, J. Loughland, F. Amante, , C. Engwerda
This study shows STING activation promotes Tr1 cell development during malaria by enhancing IFNB gene transcription and modulates this pathway with ruxolitinib.
bioRxiv · Sep 4, 2022Immunology