Author

C. Engwerda

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:clustering· 1

Frequent Co-Authors

M. J. Boyle· 3 shared B. Barber· 2 shared D. Andrew· 2 shared F. Amante· 2 shared F. de Labastida Rivera· 2 shared J. A. Engel· 2 shared J. A. Lopez· 2 shared J. Loughland· 2 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

M. J. Boyle

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Author profile →

3 papers

Recent·Most cited

Heterogeneity of the human immune response to malaria infection and vaccination driven by latent cytomegalovirus infection

R. Mukhiya, W. A. Fleischmann, J. R. Loughland, J.-A. Chan, F. de Labastida Rivera, D. Andrew, J. G. Beeson, J. S. McCarthy, B. Barber, J. A. Lopez, C. Engwerda, R. Thomson-Luque, M. J. Boyle

This study shows that latent cytomegalovirus infection reduces antibody responses to malaria infection and vaccination by altering Tfh cell subsets and their activation.

bioRxiv · Apr 28, 2024Immunology

STING activation promotes autologous type I interferon-dependent development of type 1 regulatory T cells during malaria

Y. Wang, F. Rivera, C. Edwards, T. Frame, J. A. Engel, L. Bukali, J. Na, S. Ng, D. Corvino, M. Montes de Oca, P. Bunn, M. Soon, D. Andrew, J. Loughland, F. Amante, , C. Engwerda

This study shows STING activation promotes Tr1 cell development during malaria by enhancing IFNB gene transcription and modulates this pathway with ruxolitinib.

bioRxiv · Sep 4, 2022Immunology

Th2-like T-follicular helper cells promote functional antibody production during Plasmodium falciparum infection

J.-A. Chan, F. de Labastida Rivera, J. Loughland, J. A. Engel, H. J. Lee, A. SheelaNair, B. Wines, F. Amante, L. Webb, P. Mukhopadhyay, A.-M. Patch, M. Hogarth, J. A. Beeson, J. McCarthy, A. Haque, , M. J. Boyle

The paper identifies Th2-like T-follicular helper cells as key drivers of functional antibody production during Plasmodium falciparum infection, suggesting they are targets for improved malaria vaccines.

bioRxiv · May 18, 2020Immunology