Cancer BiologybioRxivPreprint
Field cancerization impacts tumor development, T-cell exhaustion and clinical outcomes in bladder cancer
T. Strandgaard, I. Nordentoft, K. Birkenkamp-Demtroder…·L. Dyrskjot
This study shows that field cancerization in bladder cancer is linked to worse outcomes, higher mutational burden, and T-cell exhaustion, with urinary tumor DNA levels reflecting disease status.
DOI 10.1101/2023.02.20.528920