Author

T. Garcia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Immunology· 1 Microbiology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

C. Morelli· 2 shared D. Audenaert· 2 shared F. Rousseau· 2 shared J. Schymkowitz· 2 shared M. Ramakers· 2 shared S. D'Haeyer· 2 shared V. Goossens· 2 shared A. C. Bianco· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersBiophysics

C. Morelli

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

SARS-CoV-2 accessory proteins involvement in inflammatory and profibrotic processes through IL11 signaling

B. Dies, A. de Lucas-Rius, L. Mendoza, T. Garcia, R. Fernandez, J. M. Suarez, F. Milhano, F. Corrales, N. Redondo, F. Pedrucci, S. Zaldivar, M. A. Jimenez, M. Montoya, J. J. Garrido

This study identifies SARS-CoV-2 accessory proteins ORF6, ORF8, ORF9b, and ORF9c as contributors to inflammatory and profibrotic responses via IL11 signaling in lung cells.

bioRxiv · Mar 27, 2023Immunology

Tau amyloid polymorphism is shaped by local structural propensities of its protein sequence

N. Louros, M. Wilkinson, G. Tsaka, M. Ramakers, C. Morelli, T. Garcia, R. U. Gallardo, S. D'Haeyer, V. Goossens, D. Audenaert, D. R. Thal, N. A. Ranson, S. E. Radford, F. Rousseau, J. Schymkowitz

The paper identifies a C-terminal tau peptide that adopts polymorphic conformations contributing to disease-specific tau filament folds and propagation.

bioRxiv · Oct 24, 2022 · PreprintBiophysics

Mapping the sequence specificity of heterotypic amyloid interactions enables the identification of aggregation modifiers

N. N. Louros, M. Ramakers, E. Michiels, K. Konstantoulea, C. Morelli, T. Garcia, S. D'Haeyer, V. Goossens, D. Audenaert, F. Rousseau, J. Schymkowitz

The paper identifies sequence-specific rules governing heterotypic amyloid interactions and shows how they can modify amyloid assembly and contribute to neurodegenerative disease progression.

bioRxiv · Jun 4, 2021Biophysics

NEONATAL THYROXINE ACTIVATION MODIFIES EPIGENETIC PROGRAMMING OF THE LIVER

T. L. Fonseca, T. Garcia, G. W. Fernandes, T. M. Nair, A. C. Bianco

This study shows that neonatal thyroxine activation permanently alters liver epigenetic programming by modifying DNA methylation and chromatin accessibility in adult mice.

bioRxiv · Dec 7, 2020Physiology

Development of a Coronavirus Disease 2019 Nonhuman Primate Model Using Airborne Exposure

S. C. Johnston, A. Jay, J. L. Raymond, F. Rossi, X. Zeng, J. Scruggs, D. Dyer, O. Frick, J. Moore, K. Berrier, H. Esham, J. Shamblin, W. Sifford, J. Fiallos, L. Klosterman, , A. Nalca

This study infects nonhuman primates with SARS-CoV-2 via airborne exposure and compares disease progression across species.

bioRxiv · Jun 26, 2020 · PreprintMicrobiology