BiophysicsbioRxiv
A Kink in DWORF Helical Structure Controls the Activation of the Sarco-plasmic Reticulum Ca2+-ATPase
V. U. Reddy, D. K. Weber, S. Wang…·G. Veglia
This study determines the structure of DWORF and shows that a kink caused by Pro15 enables its unique activation of SERCA.
DOI 10.1016/j.str.2021.11.003