MicrobiologybioRxiv
Serum-mediated cleavage of Bacillus anthracis Protective Antigen is a two-step process that involves a serum carboxypeptidase
D. L. Goldman, E. Nieves, A. Nakouzi…·A. Casadevall
The paper shows serum cleaves Bacillus anthracis Protective Antigen in two steps: first by splitting PA83 into PA63 and PA20, then removing terminal residues via carboxypeptidase.
DOI 10.1128/msphere.00091-18