Effects of six pyrimidine analogs on the growth of Tetrahymena thermophila and their implications in pyrimidine metabolism
W.-J. Chang, Z. Harpel, J. Circelli, R. Chen, I. Chang, J. Rivera, S. Wu, Z. Wei
This study examines the effects of six pyrimidine analogs on Tetrahymena thermophila growth and their mechanisms of action, finding that different analogs inhibit growth through distinct sites and that some effects are reversible with specific nucleobases or nucleosides.
bioRxiv · Mar 29, 2023 · PreprintCell Biology