Spatiotemporal co-dependency between macrophages and exhausted CD8+ T cells in cancer
K. Kersten, K. H. Hu, A. J. Combes, B. Samad, T. Harwin, A. Ray, A. A. Rao, E. Cai, K. Marchuk, J. Artichoker, T. Courau, Q. Shi, J. Belk, A. T. Satpathy, M. F. Krummel
This study investigates the interaction between macrophages and exhausted CD8+ T cells in the tumor microenvironment, showing they form a feedback loop that promotes tumor survival.
bioRxiv · Sep 27, 2021Cancer Biology