A. A. Rao

This paper introduces an integrated optogenetic and bioelectronic platform to modulate and monitor cardiomyocyte function in vitro, showing a 14% increase in beat rate with blue light stimulation.

Cyclone is a pipeline for analyzing, evaluating, and optimizing multiparametric cytometry data, demonstrating effectiveness across multiple cytometry technologies and biological contexts.

The paper investigates early SARS-CoV-2 infection in human lung myeloid cells, finding rapid viral tropism, ACE2 dependence, and poor interferon induction, suggesting a myeloid depot for viral persistence.

This study investigates the interaction between macrophages and exhausted CD8+ T cells in the tumor microenvironment, showing they form a feedback loop that promotes tumor survival.

This study characterizes monocyte-to-macrophage differentiation in kidney cancer using scRNA-seq, linking immune phenotypes to T cell function and patient outcomes.

This study identifies distinct genetic and immunologic features of recurrent stage I lung adenocarcinoma using multiomic profiling and single-cell RNA-seq.

The paper identifies dominant immune system archetypes across 364 tumors from 12 cancer types using flow cytometry and transcriptomic data, linking them to tumor biology classifications.

The paper identifies that severe COVID-19 patients lack ISG-expressing cells and have antibodies that block their production, contrasting with mild cases.