Cell BiologybioRxivPreprint
Extracellular Matrix Stiffness Promotes Vascular Smooth Muscle Cell Calcification by Reducing The Levels of Nuclear Actin Monomers
M. C. McNeill, F. L. Chee, R. Ebrhimighaei…·M. Bond
This paper shows that increased extracellular matrix stiffness promotes vascular smooth muscle cell calcification by reducing nuclear actin monomer levels, which represses YAP-mediated osteogenic differentiation.
DOI 10.1101/2023.06.18.545506