Cell BiologybioRxiv
Spatio-temporal Control of ERK Pulse Frequency Coordinates Fate Decisions during Mammary Acinar Morphogenesis
P. Ender, P. A. Gagliardi, M. Dobrzynski…·O. Pertz
The paper shows that ERK pulse frequency controls cell fate during mammary acinar morphogenesis, with high frequency promoting survival and low frequency inducing apoptosis.
DOI 10.1016/j.devcel.2022.08.008