Author

T. J. Waybright

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1

Frequent Co-Authors

A. G. Stephen· 1 shared B. Hunt· 1 shared C. W. Johnson· 1 shared D. K. Simanshu· 1 shared J. A. Nowak· 1 shared K. M. Haigis· 1 shared M. H. Yang· 1 shared R. Agnor· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

A. G. Stephen

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintSep 20, 2022

Allosteric regulation of switch-II controls K-Ras oncogenicity

M. H. Yang, T. H. Tran, B. Hunt…·K. M. Haigis

This study shows that the K104Q mutation reduces oncogenic K-Ras activity in vivo by disrupting GEF-mediated nucleotide exchange and stabilizing switch-II helix through an allosteric network.

DOI 10.1101/2022.09.20.508702

mousegenetic perturbation / CRISPR

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