BiochemistrybioRxiv
Characterizing glucokinase variant mechanisms using a multiplexed abundance assay
S. Gersing, T. K. Schulze, M. Cagiada…·R. Hartmann-Petersen
The paper characterizes mechanisms of human glucokinase variants by analyzing their abundance and stability, identifying residues that affect metabolic stability and conformational dynamics.
DOI 10.1186/s13059-024-03238-2