T. Kado

Isoxanthohumol improves obesity and glucose metabolism via inhibiting intestinal lipid absorption with a bloom of Akkermansia muciniphila in mice

Genetic and lipidomic identification of tuberculostearic acid as a controller of mycobacterial membrane compartmentalization

The paper identifies tuberculostearic acid (TBSA) as a key lipid controlled by the gene cfa, which regulates membrane compartmentalization in Mycobacterium smegmatis.

Inositol acylation of phosphatidylinositol mannosides: a rapid mass response to membrane fluidization in mycobacteria

This study shows that mycobacteria rapidly modify phosphatidylinositol mannosides (PIMs) by adding an inositol acyl chain in response to membrane fluidization, enhancing resistance to membrane stress.

Cell wall damage reveals spatial flexibility in peptidoglycan synthesis and a non-redundant role for RodA in mycobacteria

This study investigates the role of RodA in mycobacterial cell wall synthesis under damage, showing its non-redundant function in spatially flexible peptidoglycan assembly and stress response.

The mycobacterial cell wall partitions the plasma membrane to organize its own synthesis

The paper shows that in Mycobacterium smegmatis, peptidoglycan precursors are synthesized in distinct plasma membrane domains that are separate from sites of cell wall assembly, and this partitioning is essential for ordered synthesis.