Author

C. E. Sein

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:bacteria (other)· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:development & morphogenesis· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1

Frequent Co-Authors

M. S. Siegrist· 2 shared A. Carfi· 1 shared A. Choi· 1 shared A. Garcia-Heredia· 1 shared A. Woods· 1 shared B. Whitener· 1 shared B. Ying· 1 shared C. Henry· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersMicrobiology

M. S. Siegrist

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Development of SARS-CoV-2 mRNA vaccines encoding spike N-terminal and receptor binding domains

G. Stewart-Jones, S. M. Elbashir, K. Wu, D. Lee, I. Renzi, B. Ying, M. Koch, C. E. Sein, A. Choi, B. Whitener, D. Garcia-Dominguez, C. Henry, A. Woods, L. Ma, D. Montes Berrueta, , A. Carfi

The paper develops and evaluates an mRNA vaccine, mRNA-1283, encoding SARS-CoV-2 spike N-terminal and receptor-binding domains, showing improved immunogenicity and protection against multiple variants in mice.

bioRxiv · Oct 7, 2022 · PreprintImmunology

The mycobacterial cell wall partitions the plasma membrane to organize its own synthesis

A. Garcia-Heredia, T. Kado, C. E. Sein, J. Puffal, S. H. Osman, J. Judd, T. A. Gray, Y. S. Morita, M. S. Siegrist

The paper shows that in Mycobacterium smegmatis, peptidoglycan precursors are synthesized in distinct plasma membrane domains that are separate from sites of cell wall assembly, and this partitioning is essential for ordered synthesis.

bioRxiv · Jul 6, 2020 · PreprintMicrobiology

DivIVA concentrates mycobacterial cell envelope assembly for initiation and stabilization of polar growth

E. S. Melzer, C. E. Sein, J. J. Chambers, M. S. Siegrist

This study shows DivIVA concentrates cell wall synthesis in mycobacteria to initiate and stabilize polar growth, supporting the idea that rod shape is a hardwired bacterial trait.

bioRxiv · Jun 7, 2018Microbiology