Cell BiologybioRxiv
Drug metabolism activity is a Critical Intrinsic Selector for Hepatocytes to elongate cell lifespan by using a cell-killing antibiotic
S. Akiyama, N. Saku, S. Miyata…·A. UMEZAWA
This study develops a method to expand human hepatocytes in vitro using a cell-killing antibiotic, enabling long-term culture and stable supply for drug research.
DOI 10.1186/s13287-022-02776-5