Functional and antigenic landscape of the Nipah virus receptor binding protein
B. B. Larsen, T. McMahon, J. T. Brown, Z. Wang, C. E. Radford, J. E. Crowe, D. Veesler, J. D. Bloom
This study uses deep mutational scanning to analyze how mutations in the Nipah virus receptor-binding protein affect function, receptor binding, and antibody escape, revealing constrained regions and limited antigenic variation in natural strains.
bioRxiv · Apr 17, 2024Evolutionary Biology