Author

C. E. Radford

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

J. D. Bloom· 3 shared T. C. Yu· 3 shared B. Dadonaite· 2 shared K. H. Crawford· 2 shared A. G. Farrell· 1 shared A. S. Dingens· 1 shared D. D. Ho· 1 shared D. R. Burton· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersImmunology

J. D. Bloom

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

ImmunologybioRxivMar 23, 2023

Mapping the neutralizing specificity of human anti-HIV serum by deep mutational scanning

C. E. Radford, P. Schommers, L. Gieselmann…·J. D. Bloom

This study maps the neutralizing specificity of human anti-HIV serum using deep mutational scanning to identify Env mutations affecting neutralization by polyclonal sera.

DOI 10.1016/j.chom.2023.05.025

humanproteomics

𝕏 PostBluesky

MicrobiologybioRxivOct 13, 2022

A pseudovirus system enables deep mutational scanning of the full SARS-CoV-2 spike

B. Dadonaite, K. H. Crawford, C. E. Radford…·J. D. Bloom

This paper introduces a pseudovirus system for deep mutational scanning of SARS-CoV-2 spike protein mutations, showing how they affect antibody neutralization and infection.

DOI 10.1016/j.cell.2023.02.001

virusproteomics

𝕏 PostBluesky

Evolutionary BiologybioRxivSep 17, 2022

A biophysical model of viral escape from polyclonal antibodies

T. C. Yu, Z. T. Thornton, W. H. Hannon…·J. D. Bloom

This paper introduces a biophysical model to predict viral escape from polyclonal antibodies by analyzing how mutations affect antibody activity against specific epitopes.

DOI 10.1093/ve/veac110

biophysical modelingdrug response / drug discovery

𝕏 PostBluesky