ImmunologybioRxiv
Knockout of αβ but not γδ T cells in chickens is associated with high cytotoxicity and deficiency of regulatory and helper T cells
T. von Heyl, R. Klinger, D. Aumann…·B. Schusser
This study generates chicken T cell knockout models to investigate their roles, finding that β T cell loss causes severe immunological defects while γδ T cell loss does not.
DOI 10.1002/eji.202350503