Immune response to vaccine candidates based on different types of nanoscaffolded RBD domain of the SARS-CoV-2 spike protein
D. Lainscek, T. Fink, V. Forstneric, I. Hafner-Bratkovic, S. Orehek, Z. Strmsek, M. Mancek Keber, P. Pecan, H. Esih, S. Malensek, J. Aupic, P. Dekleva, T. Plaper, S. Vidmar, L. Kadunc, , R. Jerala
This study evaluates DNA vaccines with RBD domains scaffolded by different peptides, finding that the β-annulus scaffold elicits the strongest immune response in mice.
bioRxiv · Aug 28, 2020 · PreprintImmunology