Lipid droplets control mitogenic lipid mediator production in human cancer cells
E. Jarc Jovicic, A. Pucer Janez, T. O. Eichmann, S. Koren, V. Brglez, P. M. Jordan, J. Gerstmeier, D. Lainscek, A. Golob-Urbanc, R. Jerala, G. Lambeau, O. Werz, R. Zimmermann, T. Petan
The paper shows lipid droplets regulate mitogenic lipid mediator production in cancer cells by controlling PUFAs availability through ATGL and DGAT1.
bioRxiv · Nov 25, 2021Biochemistry