Author

T. R. Horton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:rat· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. A. Upadhyay· 2 shared A. K. Boddapati· 2 shared A. Piantadosi· 2 shared E. G. Viox· 2 shared E. N. Beagle· 2 shared G. K. Tharp· 2 shared J. L. Harper· 2 shared K. L. Pellegrini· 2 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMicrobiology

A. A. Upadhyay

Mutual co-authors in cluster

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintOct 5, 2021

TREM2+ and interstitial macrophages orchestrate airway inflammation in SARS-CoV-2 infection in rhesus macaques

A. A. Upadhyay, T. N. Hoang, M. Pino…·S. E. Bosinger

This study identifies two macrophage populations driving inflammation in the lower airway during SARS-CoV-2 infection in rhesus macaques and shows baricitinib effectively reduces their influx and cytokine production.

DOI 10.1101/2021.10.05.463212

ratscRNA-seq

𝕏 PostBluesky

ImmunologybioRxivSep 16, 2020

Baricitinib treatment resolves lower airway inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques

T. N. Hoang, M. Pino, A. K. Boddapati…·Bosinger

This study shows baricitinib reduces lung inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques without affecting viral shedding or immune responses.

DOI 10.1016/j.cell.2020.11.007

ratexperimental assay

𝕏 PostBluesky