Modulation of type I interferon responses potently inhibits SARS-CoV-2 replication and inflammation in rhesus macaques
T. N. Hoang, E. G. Viox, A. A. Upadhyay…·M. Paiardini
This study shows that modulating type I interferon responses in rhesus macaques reduces SARS-CoV-2 viral load and inflammation, suggesting a potential therapeutic strategy for severe COVID-19.