T. R. Sosnick

The paper studies how stress-induced biomolecular condensation adapts to thermal environments across three yeast species, showing species-specific temperature tuning and conserved molecular features.

The paper introduces an optogenetic Lifeact variant for enhanced actin imaging, allowing light-controlled binding to reduce background and avoid cell perturbations.

This study uses HDX-MS on BtuB in E. coli outer membranes to show B12 binding destabilizes the Ionic Lock, while TonB binding has weaker effects and no pore formation is observed.

The paper shows that FRET fluorophores can cause disordered proteins to contract, explaining discrepancies between FRET and SAXS measurements of unfolded proteins.

This paper develops an optogenetic tool to control myosin VI activation with high spatial and temporal resolution, revealing how it integrates multiple signals for site-specific function.