Author

T. Serdiuk

ETH Zurich

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:cryo-EM· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Ouared· 1 shared A. Pokharna· 1 shared Aurélien Davranche· 1 shared B. M. Qureshi· 1 shared Cédric BoudouiD· 1 shared D. Ghosh· 1 shared D. Rhyner· 1 shared Dhiman GhoshiD· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperSystems Biology

A. Ouared

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2 papers

Recent·Most cited

An approach to characterize mechanisms of action of anti-amyloidogenic compounds in vitro and in situ

Patrick Stalder, T. Serdiuk, Dhiman Ghosh, Yanick Fleischmann, Liliana Malinovska, Aurélien Davranche, Walther Haenseler, Cédric Boudou, Elpida Tsika, A. Ouared, Jan Stöhr, Ronald Melki, Roland Riek, Natalie de Souza, Paola Picotti

This paper introduces a structural proteomic pipeline to study anti-amyloidogenic compounds' mechanisms in vitro and in situ, revealing off-target effects and structural interactions with α-Synuclein.

bioRxiv · Dec 18, 2023 · PreprintSystems Biology

On the pH-dependence of α-synuclein amyloid polymorphism and the role of secondary nucleation in seed-based amyloid propagation

L. Frey, D. Ghosh, B. M. Qureshi, D. Rhyner, R. Guerrero-Ferreira, A. Pokharna, W. Kwiatkowski, T. Serdiuk, P. Picotti, R. Riek, J. Greenwald

This study investigates how pH affects α-synuclein fibril polymorphism and shows that secondary nucleation is not polymorph-specific, revealing new polymorphs at pH 7.0.

bioRxiv · Jun 25, 2023Biophysics