The Iron Content of Human Serum Albumin Modulates the Susceptibility of Acinetobacter baumannii to Cefiderocol
J. Escalante, B. Nishimura, M. R. Tuttobene, T. Subils, V. Mezcord, L. A. Actis, M. Tolmasky, R. A. Bonomo, M. S. Ramirez
This paper shows that human serum albumin (HSA) increases Acinetobacter baumannii resistance to cefiderocol by modulating iron uptake and beta-lactam resistance gene expression.
bioRxiv · Aug 24, 2022Microbiology