M. Tolmasky

This paper quantifies the relationship between AAC(6')-Ib enzyme concentration and amikacin resistance in E. coli, showing a linear increase until a plateau due to protein aggregation.

This paper shows that human serum albumin (HSA) increases Acinetobacter baumannii resistance to cefiderocol by modulating iron uptake and beta-lactam resistance gene expression.

The paper shows that human serum and its components increase Acinetobacter baumannii resistance to cefiderocol by altering iron uptake and beta-lactam resistance genes.

This study shows that human serum albumin and meropenem together enhance natural transformation and gene expression in Acinetobacter baumannii, potentially promoting resistance and evolution.

This study shows that cerebrospinal fluid (CSF) enhances virulence factor expression and metabolic processes in low-virulence Acinetobacter baumannii strains.

This study evaluates 8-hydroxyquinoline analogs complexed with zinc to restore amikacin susceptibility in AAC(6)-Ib-producing Acinetobacter baumannii strains.

This study shows that natural transformation enables Acinetobacter baumannii to acquire antibiotic resistance genes from Klebsiella pneumoniae, contributing to the emergence of multi-drug-resistant strains.

The paper identifies a small molecule inhibitor of AAC(6’)-Ib using combinatorial libraries and evaluates its efficacy against antibiotic-resistant bacteria.