Author

T.-L. To

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Assay:metabolomics· 1

Frequent Co-Authors

A. Panda· 1 shared A. S. Fisch· 1 shared B. Gigliotti· 1 shared B. Reimer· 1 shared B. Reinstadler· 1 shared C. B. Clish· 1 shared D. Dias-Santagata· 1 shared G. H. Daniels· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCancer Biology

A. Panda

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Effectors enabling adaptation to mitochondrial complex I loss in Hurthle cell carcinoma

R. K. Gopal, V. R. Vantaku, A. Panda, B. Reimer, S. Rath, T.-L. To, A. S. Fisch, M. Cetinbas, M. Livneh, M. J. Calcaterra, B. Gigliotti, K. Pierce, C. B. Clish, D. Dias-Santagata, P. M. Sadow, , V. Mootha

This study identifies molecular effectors in Hurthle cell carcinoma linked to mitochondrial complex I loss, highlighting lipid peroxide scavenging as a therapeutic vulnerability.

bioRxiv · Aug 16, 2022Cancer Biology

Combinatorial G x G x E CRISPR screening and functional analysis highlights SLC25A39 in mitochondrial GSH transport

X. Shi, B. Reinstadler, H. Shah, T.-L. To, K. Byrne, L. Summer, S. E. Calvo, O. Goldberger, J. G. Doench, V. K. Mootha, H. Shen

The paper uses CRISPR screening to identify gene-by-gene and gene-by-environment interactions among mitochondrial transporters, revealing SLC25A39's role in mitochondrial glutathione transport.

bioRxiv · Sep 22, 2021 · PreprintCell Biology