Molecular BiologyScience SignalingPeer-reviewed
Distinct control of PERIOD2 degradation and circadian rhythms by the oncoprotein MDM2
Jingjing Liu, Xianlin Zou, Tetsuya Gotoh…·Carla V. Finkielstein
This study identifies MDM2 as a regulator of PER2 degradation and shows it influences circadian rhythm period length through a phosphorylation-independent mechanism.
47 citations