This study shows circadian disruption promotes pulmonary metastasis by altering ECM remodeling and YAP/TEAD-driven EMT programs in mice, with similar patterns observed in human melanoma.

DOI 10.64898/2026.04.20.719725

mousebulk RNA-seq

𝕏 PostBluesky

MicrobiologybioRxivPreprintFeb 12, 2026

White-tailed deer milk exhibits SARS-CoV-2 neutralizing antibodies and synergistic mechanisms that contribute to rapid viral RNA degradation

lorena p tobar, W Cantwell Smith, Hannah Raso…·Carla V. Finkielstein

This study identifies SARS-CoV-2 neutralizing antibodies and rapid viral RNA degradation in white-tailed deer milk, revealing distinct antiviral mechanisms compared to human milk.

DOI 10.64898/2026.02.11.705256

mouseproteomics

𝕏 PostBluesky

Molecular BiologyScience SignalingPeer-reviewedNov 13, 2018

Distinct control of PERIOD2 degradation and circadian rhythms by the oncoprotein MDM2

Jingjing Liu, Xianlin Zou, Tetsuya Gotoh…·Carla V. Finkielstein

This study identifies MDM2 as a regulator of PER2 degradation and shows it influences circadian rhythm period length through a phosphorylation-independent mechanism.

47 citations

humanproteomics

𝕏 PostBluesky