Cell BiologybioRxivPreprint
Soluble ZP2 N-terminal fragments activate CatSper-dependent Ca2+ entry and regulate motility and acrosomal exocytosis in mammalian sperm
Caroline Wiesehöfer, Lorena Sunjic, Lara Suetin…·Gunther Wennemuth
This study identifies soluble ZP2 N-terminal fragments as activators of CatSper-dependent Ca2+ entry, regulating sperm motility and acrosomal exocytosis in mice and humans.