NeuroscienceMolecular PsychiatryPeer-reviewed
Glutamatergic dysfunction leads to a hyper-dopaminergic phenotype through deficits in short-term habituation: a mechanism for aberrant salience.
Marios C. Panayi, Thomas Boerner, Thomas Jahans-Price…·David M. Bannerman
This study shows that GluA1 dysfunction leads to impaired short-term habituation, resulting in a hyper-dopaminergic phenotype in the nucleus accumbens, which may contribute to aberrant salience in schizophrenia.
21 citations