Author

Tianzhi Wu

University of California, San Francisco

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:metagenomics· 1

Frequent Co-Authors

Arnold R. KriegsteiniD· 2 shared Jingjing LiiD· 2 shared Tanzila MukhtariD· 2 shared Cheng Wang· 1 shared Clara SiebertiD· 1 shared Erqiang HuiD· 1 shared Guangchuang YuiD· 1 shared Guolong ZuoiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersNeuroscience

Arnold R. KriegsteinORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

NeuroscienceNature BiotechnologyPeer-reviewedJan 27, 2026

Single Cell Proteomics in the Developing Human Brain

Tianzhi Wu, Lihua Jiang, Tanzila Mukhtar…·Jingjing Li

This study develops a single-cell proteomics workflow to analyze the developing human brain, revealing transcriptome-proteome discordance and identifying molecular vulnerabilities in neurodevelopmental disorders.

23 citationstop 1%

humanproteomics

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NeuroscienceNature CommunicationsPeer-reviewedJul 1, 2025

α7 nicotinic acetylcholine receptors regulate radial glia fate in the developing human cortex

Tanzila Mukhtar, Clara Siebert, Yuejun Jessie Wang…·Arnold R. Kriegstein

This study shows that α7 nicotinic acetylcholine receptors influence radial glia fate in human cortical development, with nicotine exposure altering neuronal differentiation and RG proliferation.

7 citations

humanbulk RNA-seq

𝕏 PostBluesky

BioinformaticsThe InnovationPeer-reviewedJul 1, 2021

✦ In-depth digest

clusterProfiler: An universal enrichment tool for functional and comparative study

Tianzhi Wu, Erqiang Hu, Shuangbin Xu…·Guangchuang Yu

clusterProfiler performs over-representation (Fisher's exact test) and gene set enrichment analyses on Gene Ontology, KEGG, and user-supplied annotations, supporting non-model organisms, multi-condition comparisons, and ggplot2-based visualization.

12,469 citationstop 1%

multiple speciesmetagenomics

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