BioinformaticsbioRxiv
Automated and accurate estimation of gene family abundance from shotgun metagenomes
Stephen Nayfach, Patrick H. Bradley, Stacia K. Wyman…·Thomas J. Sharpton
This paper develops ShotMAP, a metagenome annotation pipeline, and evaluates its performance on marine and gut microbiome data, finding functional differences in Crohn's disease patients.
DOI 10.1371/journal.pcbi.1004573