BiochemistryFEBS JournalPeer-reviewed
Kinetic and structural characterization of human NUDIX hydrolase NUDT15 and NUDT18 as catalysts of isoprene pyrophosphate hydrolysis
Emma Rose Scaletti, Judith E. Unterlass, Ingrid Almlöf…·Ann‐Sofie Jemth
This study identifies NUDT15 and NUDT18 as human enzymes that hydrolyze isoprene pyrophosphates, with NUDT18 showing the highest catalytic efficiency for geranyl pyrophosphate.
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