Author

Ann‐Sofie Jemth

Science for Life LaboratoryORCID 0000-0002-7550-1833Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1

Frequent Co-Authors

Dante RotiliiD· 1 shared Despina Kapsitidou· 1 shared Emma Rose ScalettiiD· 1 shared Eri van Berkum· 1 shared Fredrik KlingegårdiD· 1 shared Gabriel Tidestav· 1 shared Ingrid Almlöf· 1 shared Jonas Malmström· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

Dante RotiliORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintJun 13, 2025

A cell-based degrader assessment platform facilitates discovery of functional NUDT5 PROTACs

Seher Alam, Maria Joao Almeida A Silva Pires, Gabriel Tidestav…·Mikael Altun

This paper introduces a cell-based platform to assess PROTACs targeting NUDT5, identifying a VHL-dependent degrader despite poor in vitro binding and showing CRBN-dependent degraders are ineffective.

1 citation

humanproteomics

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BiochemistryFEBS JournalPeer-reviewedJun 29, 2024

Kinetic and structural characterization of human NUDIX hydrolase NUDT15 and NUDT18 as catalysts of isoprene pyrophosphate hydrolysis

Emma Rose Scaletti, Judith E. Unterlass, Ingrid Almlöf…·Ann‐Sofie Jemth

This study identifies NUDT15 and NUDT18 as human enzymes that hydrolyze isoprene pyrophosphates, with NUDT18 showing the highest catalytic efficiency for geranyl pyrophosphate.

2 citations

humanexperimental assay

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