Author

Tsering D Lama

Columbia University Irving Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:database / resource· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Mariko F. TagaiD· 3 shared Philip L. De JageriD· 3 shared David Alan BennettiD· 2 shared Hans‐Ulrich KleiniD· 2 shared Masashi FujitaiD· 2 shared Vilas MenoniD· 2 shared Ya ZhangiD· 2 shared Aiqun LiiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersNeuroscience

Mariko F. TagaORCID

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Author profile →

3 papers

Recent·Most cited

High-Dimensional Multi-omic Mapping of Post-Mortem Human Brain Using Iterative Indirect Immunofluorescence Imaging on Xenium-Processed Tissues

Berke Karaahmet, Tsering D Lama, Anqi Wang, Wenqing Cao, Vilas Menon, Hans‐Ulrich Klein, David Alan Bennett, Philip L. De Jager, Ya Zhang, Mariko F. Taga

The paper develops a post-processing workflow combining Xenium spatial technology with 4i imaging to enable multi-omic mapping of post-mortem human brain tissue, focusing on pathological microenvironments.

bioRxiv · Sep 23, 2026 · PreprintNeuroscience

A systems approach uncovers drivers of the multifocal emergence of an astrocyte state contributing to cognitive decline in Alzheimer's disease

Natacha Comandante-Lou, Tsering D Lama, Sarah E. Heuer, Kevin W. Chen, Jinho Kim, Jinglong Zhang, Bin Hu, Shuhui Liu, Swagata Dey, Kristen Brennand, Julie A. Schneider, Lisa L. Barnes, Bin Zhang, Minghui Wang, Hongyan Zou, , Philip L. De Jager

The paper identifies a novel astrocyte state linked to cognitive decline in Alzheimer's disease and validates its regulators through multi-modal analysis and mechanistic experiments.

bioRxiv · Feb 24, 2025 · PreprintNeuroscience

GWAS highlights the neuronal contribution to multiple sclerosis susceptibility

Lu Zeng, Atlas Khan, Tsering D Lama, Tanuja Chitnis, Howard L. Weiner, Gao T. Wang, Masashi Fujita, Frauke Zipp, Mariko F. Taga, Krzysztof Kiryluk, Philip L. De Jager

This study identifies 236 MS susceptibility variants and highlights neuronal and glial dysfunction as key factors in MS susceptibility.

medRxiv · Dec 4, 2024 · PreprintGenetic & Genomic Medicine