Lu Zeng

This study investigates the genetic overlap between inflammatory bowel disease and Alzheimer's disease, finding distinct myeloid cell-specific risk factors and some protective associations.

This study identifies 236 MS susceptibility variants and highlights neuronal and glial dysfunction as key factors in MS susceptibility.

The paper identifies cell-type and cell-subtype specific eQTLs in aging human cortex, revealing variant effects on gene expression and disease associations.

The paper identifies transcriptomic changes in normal aging brains that resemble Alzheimer's disease in specific subgroups, suggesting early molecular links between aging and LOAD.

This study analyzes the tissue-specific age dependence of cell receptors involved in SARS-CoV-2 infection and identifies key regulators and host processes hijacked by the virus.

This study analyzes genetic variants associated with longevity and age-related diseases to understand their impact on gene expression.

The paper compares gene regulations in 'healthy' and 'common' aging using GTEx data to identify differences and connections with age-related diseases.

The paper presents the tuatara genome, highlighting its evolutionary significance and unique features compared to other vertebrates.

The paper introduces CARP, an ab initio pipeline for identifying and annotating TEs and segmental duplications in genome assemblies, showing it outperforms RepeatModeler.

The paper analyzes the genome-wide impact of transposable elements on gene regulation, finding that Alu elements are associated with upregulated gene expression and contribute more to regulatory regions than ancient TEs.