Author

Tuong Nghi Duong

Innovative Genomics Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Daniel K. NomuraiD· 2 shared Qian Shao· 2 shared Edward Pandji· 1 shared Inji ParkiD· 1 shared Lauren M. OrriD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 8 mutual co-author links

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2 shared papersBiochemistry

Daniel K. NomuraORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintDec 14, 2025

Discovery of Non-Degradative Covalent Molecular Glues for Transcriptional Reprogramming

Tuong Nghi Duong, Edward Pandji, Qian Shao, Daniel K. Nomura

This study identifies ZD-1-186, a non-degradative molecular glue that rewires BCL6 proximity to suppress MYC and induce tumor-suppressive genes in lymphoma cells.

3 citations

humanproteomics

𝕏 PostBluesky

BiochemistryJournal of the American Chemical SocietyPeer-reviewedAug 28, 2024

Covalent 14-3-3 Molecular Glues and Heterobifunctional Molecules Against Nuclear Transcription Factors and Regulators

Qian Shao, Tuong Nghi Duong, Inji Park…·Daniel K. Nomura

This study identifies a covalent ligand, EN171, that enhances 14-3-3 interactions with transcription factors like ER, YAP, and TAZ, inhibiting their activity and demonstrating its use in heterobifunctional molecules to sequester nuclear substrates.

35 citationstop 4%

experimental assaydrug response / drug discovery

𝕏 PostBluesky