Preclinical Comparison of DMT and 5-MeO-DMT Reveals Behavioral Dissociation, Distinct TrkB Activation and Differential Plasticity Profiles
Orr Shahar, Alexander Botvinnik, Masha Chaykin…·Bernard Lerer
This study compares the acute pharmacology and long-term neuroplastic effects of DMT and 5-MeO-DMT in mice, showing distinct behavioral and molecular outcomes.