ImmunologybioRxivPreprint
An unconventional mechanism of IL-1β secretion that requires Type I IFN in lupus monocytes
S. Caielli, P. Balasubramanian, J. Rodriguez-Alcazar…·V. Pascual
The paper identifies an unconventional IL-1β secretion mechanism in lupus monocytes requiring Type I IFN, involving mitochondrial RNA and the NLRP3 inflammasome.
DOI 10.1101/2023.08.03.551696