Inhibition of the TLR4 signalling pathway with TAK-242 reduces RSV infection and cytokine release in primary airway epithelial cells
L. Broadbent, G. C. Roberts, J. D. Coey…·the Breathing Together Consortium
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Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
5 papers
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L. Broadbent, G. C. Roberts, J. D. Coey…·the Breathing Together Consortium
C. G. G. Bamford, L. Broadbent, E. Aranday Cortes…·The Breathing Together Consortium
This study investigates how viral and host factors influence SARS-CoV-2 evolution in vitro, identifying genetic changes and their impact on viral fitness in different cell types.
L. Broadbent, H. Guo Parke, L. J. Ferguson…·U. F. Power
This study compares the therapeutic efficacy of ALX-0171 and palivizumab against RSV infection in a human bronchial epithelial cell model, showing ALX-0171 is more potent at neutralizing virus but less effective at reducing viral genomic copies.
L. Broadbent, S. Manzoor, M. Zarcone…·U. F. Power
This study compares two commercial media for culturing primary nasal epithelial cells and evaluates their impact on cell morphology, physiology, and RSV infection outcomes.
K. Ezzat, M. Pernemalm, S. Palsson…·S. E. Andaloussi
This study shows that viruses form protein coronas that affect infectivity, immune activation, and amyloid aggregation, linking viral and amyloid pathologies.