Cancer BiologybioRxiv
Predicting master transcription factors from pan-cancer expression data
J. Reddy, M. A. S. Fonseca, R. I. Corona…·K. Lawrenson
This paper introduces CaCTS, an algorithm that identifies candidate master transcription factors (MTFs) across 34 cancer types using RNA-seq data, revealing novel MTFs and functional groupings.
DOI 10.1126/sciadv.abf6123