Cellular heterogeneity during mouse pancreatic ductal adenocarcinoma progression at single-cell resolution
A. N. Hosein, H. Huang, Z. Wang, K. Parmar, W. Du, J. Huang, A. Maitra, E. Olson, U. Verma, R. A. Brekken
This study uses single-cell RNA sequencing to analyze cellular heterogeneity in mouse pancreatic ductal adenocarcinoma progression, identifying epithelial-to-mesenchymal transition, inflammatory macrophages, and fibroblast subtypes.
bioRxiv · Feb 4, 2019Cancer Biology