Author

A. N. Hosein

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1

Frequent Co-Authors

A. Maitra· 2 shared A. A. Singhi· 1 shared B. Ghosh· 1 shared C. L. Haymaker· 1 shared E. Olson· 1 shared G. Dangol· 1 shared H. Clevers· 1 shared H. Huang· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

A. Maitra

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2 papers

Recent·Most cited

Cancer BiologyGastroenterologyPeer-reviewedApr 1, 2022

Loss of Rnf43 accelerates Kras-mediated neoplasia and remodels the tumor immune microenvironment in pancreatic adenocarcinoma

A. N. Hosein, G. Dangol, T. Okumura…·A. Maitra

This study shows that loss of Rnf43 accelerates Kras-driven pancreatic cancer and alters the tumor immune microenvironment by increasing lymphocytes and immune checkpoint expression.

DOI 10.1053/j.gastro.2021.12.273

mousebulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivFeb 4, 2019

Cellular heterogeneity during mouse pancreatic ductal adenocarcinoma progression at single-cell resolution

A. N. Hosein, H. Huang, Z. Wang…·R. A. Brekken

This study uses single-cell RNA sequencing to analyze cellular heterogeneity in mouse pancreatic ductal adenocarcinoma progression, identifying epithelial-to-mesenchymal transition, inflammatory macrophages, and fibroblast subtypes.

DOI 10.1172/jci.insight.129212

mousescRNA-seq

𝕏 PostBluesky