Species-specific roles for the MAFA and MAFB transcription factors in regulatingislet β cell identity
J. Cha, X. Tong, E. M. Walker, T. Dahan, V. Cochrane, S. Ashe, R. Russell, A. B. Osipovich, A. M. Mawla, M. Guo, J.-h. Liu, M. O. Huising, M. A. Magnuson, M. Hebrok, Y. Dor, R. Stein
The paper investigates the species-specific roles of MAFA and MAFB in maintaining β cell identity, showing MafA in mice and MAFB in humans repress non-β cell hormones like GAST.
bioRxiv · Oct 20, 2022Cell Biology