Resolving the Dynamic Motions of SARS-CoV-2 nsp7 and nsp8 Proteins Using Structural Proteomics
V. Courouble, S. Dey, R. Yadav, J. Timm, J. Harrison, F. X. Ruiz, E. Arnold, P. R. Griffin
This study uses HDX-MS and XL-MS to analyze the structural dynamics of the full-length SARS-CoV-2 nsp7:nsp8 complex, revealing conformational flexibility and a different assembly model compared to SARS-CoV.
bioRxiv · Mar 6, 2021 · PreprintBiophysics